PlotEdit
A multinational six-member crew aboard the International Space Station performs a successful capture of a space probe returning from Mars with a soil sample. The crew is tasked with studying the sample, which could prove to be the first evidence of extraterrestrial life. After extracting a single-cell from the sample, British biologist Hugh Derry is able to revive the dormant organism with atmospheric adjustments and glucose feed. It grows into a multi-celled organism quickly and reacts to stimuli. The crew discovers that each cell in the organism is a myocyte, neuron and photoreceptor, all at the same time. One of the scientists remarks that the organism is "…all muscle, all brain and all eye."
The organism, now named Calvin by school children in America, begins to evolve and grow quickly. After an atmospheric accident in the lab, Calvin becomes dormant. Concerned with its survival, Hugh attempts to revive Calvin with a mild electric shock. Calvin re-animates, and grabs hold of Hugh’s right hand, ultimately crushing it as Hugh struggles to get free. Calvin shows problem solving skills and escapes the containment cube into the room with Hugh. While it devours a lab rat and immediately evolves and grows in size, American engineer Rory Adams enters the room and rescues Hugh. However, sensing his presence, Calvin latches onto Rory’s leg. The crew captain, Dr. Miranda North from CDC, locks Rory inside the room to keep Calvin in containment. Rory manages to remove Calvin from his leg and begins to attack it with a handheld incinerator. Calvin shows remarkable resilience to fire and evades Rory’s attacks until the incinerator runs out of fuel. Calvin then attacks Rory and forces its way into his mouth, killing him from the inside. Emerging from Rory’s mouth, even more evolved and larger, Calvin then manages to escape from the room through an emergency fire suppression vent. Hugh theorizes that the lack of breathable air on Mars is probably what kept the organism dormant until that point.
Finding their communication to Earth cut off, a Russian commander Katerina Golovkina dons an EVA suit to perform a space walk and fix the antenna. Calvin consumed ISS coolant as a source of nutrition, escapes through a valve on the antenna and attacked Katerina outside the ISS. The attack ruptured Katerina’s EVA suit’s coolant system, effectively drowning her inside her suit. Calvin attempts to enter the station through the thrusters. An attempt to stop Calvin results in the ISS entering a decaying orbit. Engineer and Japanese pilot Sho Murikami informs the crew that they need to use the remaining fuel to get back into a standard orbit, but that it would allow Calvin back into the station. The crew formulate a plan to try make Calvin dormant by sealing themselves into one module and venting the atmosphere from the rest of the station. When Hugh suddenly enters cardiac arrest, the crew manage to resuscitate him only to realize that Calvin had attached himself to Hugh’s leg and was feeding off of him. Now having grown into a much larger tentacled creature, Calvin attacks the remainder of the crew. Sho makes a run for the sleeping cabin and seals himself inside his pod as Calvin attempts to crack the glass and get to him. Miranda and crew doctor, David Jordan, realize that Calvin has ingested one of the vital sign trackers on Hugh’s suit and begin to track him. Using Hugh’s body and blood as bait, they lure Calvin away from Sho and trap it in a module to deprive it of oxygen.
Having received the SOS call just prior to the damage to the ISS communication system, Earth Control send an unmanned Soyuz capsule as a fail-safe plan to push the station out towards deep space, which was a protocol pre-designed by Dr. Miranda North. The capsule docks against the module where Calvin was contained and start pushing the station into deep space. Presuming it to be a rescue attempt, Sho leaves his pod and rushes to board the arriving ship. He enters the module and attempts to manually force open the hatch to enter the capsule. As soon as he opens the hatch, Calvin attacks him. The crew tries to save Sho, but Sho’s action had causes a breach that result in the docks venting air out into space, and it progressively worsen until the capsule detaches from the station, sends the capsule spiralling back into ISS, crashing into the station.
The incident causes the temperature and oxygen levels in the ISS to fall rapidly. David and Miranda, the only survivors, realize that the incident has also caused them to re-enter a decaying orbit that will culminate in re-entry into Earth’s atmosphere. Aware that Calvin could possibly survive re-entry, David recalls the two emergency escape pods that are programmed to auto-pilot towards Earth and plans to lure Calvin into one of the pods before manually overriding the system to fly into deep space, whilst letting Miranda escape in the other pod to return to Earth.
David leads Calvin into his pod and launches into space as Miranda launches hers. Her pod hits debris from the ISS and is knocked off course. Calvin attacks David as he struggles to send his pod into deep space. The two pods then divert. The earthbound pod performed a re-entry and lands with parachute in a body of water near two fishermen. As they approach the pod, it is revealed to be David’s, with David encased and trapped in a black goo-like substance created by Calvin. Meanwhile Miranda screams helplessly as her navigation system fails and her pod is hurled into deep space. David, still alive, tries to warn the fishermen to not open the pod. As the fishermen open the pod door, more fishing boats arrive. The screen then cuts to black.